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The pre-Btzinger Complex (preBtC) is responsible for generating the inspiratory rhythm through pacemaker glutamatergic neurons, which project to the rostral ventral respiratory group (rVRG), a group of pre-motor neurons situated in the ventral region of the medulla (Yang C

These cytokines can promote cognitive dysfunction as they are able to disrupt the blood-brain barrier (BBB), allowing proinflammatory cytokines (355) to translocate into the brain and promote inflammation ( Figure 10 )

One possibility is that intestinal epithelial cells may be exposed to higher concentration of intact aspirin immediately following oral administration compared with the measured plasma levels, which reflects concentration after first-pass metabolism

Cell 55 , 332341 (2014)

The consequences of phosphorylation and eventual hyperphosphorylation of Tau can lead to the loss of its normal homeostatic functions and is increasingly cytotoxicity (Liu et al., 2020)

the pH of the mixture was adjusted at 8.5 with DIEA for optimum coupling